Simco Wildlife Area lies in the southeastern corner of Coshocton County, approximately 3 miles south of the town of Coshocton. Access to the area may be gained from State Route 83 and Township Road 276, which runs east-west through the area. Over 97 percent of the land (837.4 acres) is forested. The remaining three percent (20.5 acres) is wetlands and ponds.
White-tailed deer, squirrels, rabbits, wild turkey, and ruffed grouse are the primary species of interest. Furbearers including beaver, raccoon, opossum, muskrat, mink, and skunks are present. The water impoundments have been stocked with bass, bluegill, and channel catfish. Deer and turkey hunting may be productive throughout the area. Grouse and rabbit hunting may be productive in the brush land areas. Good squirrel hunting may be encountered on most of the area. Simco Wildlife Area also presents good opportunities for trapping furbearers.